Image:Manguinhos_fiocruz2.jpg|thumb|right|260px|Façade of the Moorish Revival|Neo-Mouresque Palace of Manguinhos, seat of the Instituto Oswaldo Cruz in Rio de Janeiro.
The '''Oswaldo Cruz Foundation''' (Portuguese language|Portuguese
'''''Fundação Oswaldo Cruz''''', also known as '''FIOCRUZ''') is a scientific institution for research and development in biological sciences located in Rio de Janeiro
, it is considered one of the world's main public health
research institutions. It was founded by Dr. Oswaldo Cruz
, a noted physician and epidemiologist.
The organization started in 1898 as the '''Federal SeroTherapy Institute''' with the objective of developing serum and vaccines against the bubonic plague
It was located outside of Rio de Janeiro
The institute’s activities, however, changed from simple production into research and experimental medicine, especially...